The Cellular Neurobiology and Regeneration Laboratory lead by Dr. Francisca Bronfman, studies the cellular and molecular mechanisms that regulate the connectivity between neurons and their regeneration after injury. Exercise, hormones, and certain drugs increase the plastic and regenerative capabilities of the nervous system after injury (i.e. stroke and neurodegenerative diseases). These responses are associated with specific neurotrophin membrane receptors. Dr. Bronfman studies the contribution of the endosomal system to the response to neurotrophins in axons and dendrites in different neuronal systems, both in the central and peripheral nervous systems. The laboratory is also focused on the plastic changes that occur after stroke as well as the development of drugs or derivatives of natural extracts that can modulate trophic brain systems to induce reparation of the nervous system following stroke.
Investigator in charge: Francisca Bronfman