Regenerative biology

Investigación

The amphibians, unlike the mammals (mice, human beings) possess enormous regenerative capacities. The frogs as Xenopus laevis, in the tadpole stage, are capable of regenerating the spinal cord, capacity that gets lost in the adult state. On the other hand the salamanders, in its adult state can regenerate complete limbs, spinal cord, heart, and the retina. Our interest is to understand the differences between the regenerative species (amphibians) and the non-regenerative (mammals), through the study of the cellular, molecular and genetic bases of the regeneration of the nervous system in amphibians. To determine the basic mechanisms of the regeneration of the spinal marrow in amphibians can be useful to become able to induce the regeneration of this tissue in mammals and then, to design new therapies. Diseases such as Parkinson, Alzheimer, and spinal cord injury derive from neuronal damage and death. The aim of regenerative medicine is to provide an ailment for these and other diseases that require regeneration of the damaged tissue. Its promise lies in two main strategies: (i) cell-based therapies, which consist in the in vivo culturing and differentiation of stem cells followed by their transplantation into patients